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Chinese scientists create mutant Ebola virus in lab
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Chinese scientists create mutant Ebola virus in lab
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Chinese scientists have indeed engineered a virus in a lab that contains parts of the Ebola virus. This modified virus caused severe symptoms and fatalities in a group of hamsters. Let me provide you with more details:

The Experiment:
Researchers at Hebei Medical University in China conducted this study.
They combined a contagious disease found in livestock with a protein from the Ebola virus.
The protein they used is called glycoprotein (GP), which plays a crucial role in helping the Ebola virus enter and infect host cells.
The goal was to find animal models that could safely mimic Ebola symptoms in a lab setting.
To work around the high-security requirements of handling Ebola (which usually requires Biosafety Level 4 facilities), they used a different virus called vesicular stomatitis virus (VSV).
The engineered VSV carried part of the Ebola virus (GP) and allowed it to infect cells and spread throughout the body.
The researchers infected hamsters with this modified virus to observe its effects.
The hamsters that received the lethal injection developed severe systemic diseases similar to those observed in human Ebola patients.
One particularly horrific symptom was the development of secretions in their eyes, which impaired their vision and scabbed over the surface of their eyeballs.
Female Syrian hamsters showed decreased rectal temperature and up to 18% weight loss, and they all died between two and three days.
Male hamsters lost 15% weight and succumbed to the disease within three and a half days.
However, two male hamsters survived and gained 20% more weight than before infection.
The virus accumulated in various organs, including the heart, liver, spleen, lung, kidney, stomach, intestines, and brain tissues1.
While this experiment might raise concerns about lab safety, the researchers’ intention was to find suitable animal models for studying Ebola. By using hamsters, they hope to advance our understanding of the virus and its treatment. It’s essential to strike a balance between scientific progress and safety precautions when working with dangerous pathogens.
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